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New SENTRY® Fiproguard® Plus has the same active ingredients as FRONTLINE® Plus but costs less.* SENTRY® Fiproguard® Plus contains fipronil, the No. 1 veterinarian-recommended active ingredient, and (s)-methoprene to protect against fleas, flea eggs, flea larvae, ticks and chewing lice. Fast acting and long lasting, SENTRY® Fiproguard® Plus stops the reinfestation cycle by killing flea eggs and larvae and also helps to protect your pets and family from illness by killing ticks that may transmit Lyme disease.